Thank you for choosing the most precious article. I hope your time investment in this discussion will not go in vain! What do you think the article is all about? Have you felt that article will go on the rails of routine? Not a chance. You may have searched and searched for the liver, but you may not be pleased with the information you’re browsing. Now, based on your experience you have your own style of quoting liver, maybe as the largest internal organ in the human body or it has two lobes – right and left; blah, blah, blah! But your thankfulness of study will not stop here, right? So to meet your interest I’ll be asking you now (also later I’ll describe) what does the liver do?
Your eye has witnessed many of the cases of liver transplantation and your ears listened that the liver gets a stroke with the consumption of alcohol or may be due to diabetes. Though it’s true, how do you think that liver will be affected? Do liver has any importance in the human body? Before you feel like I’m hammering your brain with questions, let me give you quick facts on the liver.
Quick Recap Points on Liver:
- Liver is perfectly positioned in upper right abdominal cavity
- It’s not just an undivided organ; liver divides into right and left lobes. Right lobe has further divisions and doesn’t involve in any of the liver functions.
- The liver has set its position with the help of co-internal-organs – stomach, right kidney, and duodenum colon.
- As your smartphone is powered by so many configurations, so does the liver and the processors, those power up liver health include ligaments, functioning system, and fluid system.
- Liver’s ecosystem balances on two main blood vessels – portal vein and hepatic artery.
- Weighing about 1.44 to 1.66 kilograms or 3.2 to 3.7 lbs, liver extends to the width of 15cm.
- Another interesting fact is if you hit with your palm just above the stomach and below the chest, you hear a sound and yes, that’s where the liver exists!
Wow! Now you have known much about the liver. Do you think so? I just gave a sample of “where is the liver? What are blood vessels of the liver? And, where does it exist?” You have just studied the outline on the liver. Now the core structure of your liver and on your liver begins.
What Does the Liver do?
Whatever you may think about the liver is secondary. The primary part is functions of liver and their contribution in triggering your health. The liver has some purpose in your body. The purpose is functioning which embraces Secretory, Vascular and Metabolic.
Liver stands itself for bile secretion. Bile is an alkaline fluid flows with the concentration of organic molecules such as bilirubin, phospholipids and bile acids, electrolytes and water. Through the phenomenon of secretion, many of the unnecessary products including faeces are pushed out of the body.
Any internal organ in the human body is not at all feels or will be left alone, as each organ supports the other one. Similarly liver retrieves the output from cardiac to 30%. Hence, it became a vascular function organ. The vascular function of the organ is dynamic as it stores and releases blood, just like a reservoir within a standard flow.
Who do you call an overachiever within your circle? You may now think on this. But liver too has overachievers called Hepatocytes. Why so? Because their role in the playfield of liver health is to synthesize the molecules. This is because to give a hand to homeostasis, which will convert molecules from one form to the other and give a stability to balance energy. The liver does not end its role in metabolism in two lines.
You may be worried due to increased glucose levels in your blood but liver takes care of it. During short as well as long hours of time, the liver will take up the challenge saying, “Hey! I’m here to maintain blood sugar levels perfectly.”
The liver is a house to hepatocytes those will lay the routes of metabolism in different directions and trigger the active or inactive state of various enzymes depending on the rise or fall of the sugar levels bringing them to normal range.
Liver attracts the uniqueness of lipid metabolism and to stabilize liver health in terms of fat metabolism, it includes:
- Triglycerides are oxidized with liver’s activeness to illuminate the energy. Liver simplifies the complex fatty acids those are a call for hepatocytes and acetoacetate flows into the blood from the tissues.
- Liver synthesizes Lipoproteins in vast.
- Adipose tissue stores the triglyceride and fatty acids. These are converted from the proteins and carbohydrates.
- Cholesterol and Phospholipid amalgamate in the liver and are excreted through bile if found any excess after supplying throughout the body.
- Amino acids undergo Transamination and deamination. The absence of nitrogenous part during these processes will be converted to glucose or lipids.
- Urea synthesis removes excess ammonia from the body. A central nervous system can be observed if ammonia is not railed out of the body.
- Non-essential amino acid production.
- Hepatocytes hold the synthesis of plasma proteins on their shoulders. A safeguard to blood coagulation, liver goes rival against the clotting factors.
The concept of liver functions and its major contribution is what now you’re glad about. But, is this what liver does! Are you felt enough with the context? You may not. Still, you want something more on “what does the liver do?”, if I’m exaggerating your guess.
Elevated Liver Enzymes
Do you think that there will not be any elevated liver enzymes as liquid flow? Liver functions on three fluids – blood, bile and lymph. These three fluid systems embrace the liver functioning.
Bile acids concentrated in bile juice will hold a responsibility for digestion and making fats soluble in the small intestine. Hepatocyte synthesizes cholesterol and bile acids are its derivatives. Cholesterol is completely ionized into chenodeoxycholic and cholic acids. Bile juice dilutes these acids conjugating to amino acids.
The flavour of bile acid is amphipathic which means it has both polar and hydrophobic features. This nature, amphipathic derives two more functions:
Lipid Aggregated Emulsification:
Dietary fat are thoroughly rinsed into droplets with the action of detergent by the bile acids.
Lipid Solubility and transportation in Aqueous:
Monoglycerides will make lipids soluble which are water-suspended.
Homeostasis of Cholesterol:
Cholesterol becomes simpler, simpler and simpler through Hepatocytes.
50% of lymph formation in the body is through the liver. Sinusoidal endothelial cells will result in pore formation so as to flow the blood smoothly into the gap in between hepatocytes and endothelium, thus resulting in Lymph formation. If sinusoidal pressure increases then there will be an increase in production rate of Lymph.
Blood Flow in the Liver:
Liver receives blood from five internal organs – spleen, pancreas, small and large intestines of digestive tract and stomach. This will trigger the liver to be active to break down the complex molecules through bile production and reducing the risk of fatty liver. The liver gets the 1500ml per minute blood from 1/3 hepatic artery and 2/3 portal vein.
Ligaments in Liver
Connective tissue Ligament connects in a tougher way to the two cartilages or bones. The liver is a rich in standardizing these ligaments. The three ligaments – Falciforn, Coronary and lesser omentum will elevate liver and by the end of this, it may be a convincible answer to “what does the liver do?”
It will be anterior to the wall of the liver. This ligament is what makes a separation between the right lobe and left lobe.
Coronary ligament splits into posterior and anterior layers. The formations of these two layers are due to the peritoneum orientation as it reflects on the liver. Here where falciforn contributes its part in these layer formations.
Lesser omentum is a soft, delicate tissue that extends to stomach and duodenum’s first part.
The ligaments will determine the liver’s designation and its area in the body. Now I must say big congratulations to you as the probability of your knowledge on liver has reached to 70%. Rest 30% is yet to be discussed. This is not a clinic or hospital we’re running to explain the clinical terms. If you’re interested then you may go in deep study. Your question of what does the liver do has got a very big answer.
The other two liver enzymes are left and a glance at liver transplantation. Glisson’s Capsule and Hilus are enzymes.
Liver’s functional units are lobules. Hepatic cells in millions are structured for the lobule formation. A layer of connective tissue will extend the liver’s structure in accompanying nerves, ducts and arteries. This formed the Glisson Capsule in the liver.
It’s a groove through which blood vessels, nerve, fibers, and ducts leave or enter into the liver’s surface.
You have a research data in your mind on a 360-degree look of the liver. However, few complications are coming up damaging the liver health. Liver transplantations have bloomed across many clinics and multi-speciality hospitals as there is a number of cases of liver failure.
According to the European Transplant Registry 2012, liver transplantation is helping 80% of individuals by adding 5 years to their life and to 70% of them, it is adding 10 years life. What a great to know! Abnormal liver function is the cause of maybe our own negligence in having the healthy diet or may be due to external disturbances those are vibrating negatively to the internal organs.
What does the liver do, what is its functioning and other queries now are in your mind. Your negligence on food diet and exercises should not be avoided because life is beautiful. I Hope that your investment of time is not wasted but you have learnt something about one of your body organs, liver. A conscious thought, a conscious health is a sign of intelligence in life’s bubble.